{"id":1513,"date":"2019-11-01T14:49:04","date_gmt":"2019-11-01T14:49:04","guid":{"rendered":"http:\/\/practicalhealthpsychology.com\/?p=1513"},"modified":"2025-11-04T14:24:18","modified_gmt":"2025-11-04T14:24:18","slug":"n-of-1-studies-what-can-we-learn-by-studying-a-single-case","status":"publish","type":"post","link":"https:\/\/practicalhealthpsychology.com\/ro\/2019\/11\/n-of-1-studies-what-can-we-learn-by-studying-a-single-case\/","title":{"rendered":"Studii de tip N-of-1: Ce putem afla din studierea unui singur caz?"},"content":{"rendered":"<p><b>Marie Johnston \u0219i Derek Johnston, University of Aberdeen, Scotland<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Adesea practicienii vor s\u0103 g\u0103seasc\u0103 solu\u021bii pentru probleme referitoare la o persoan\u0103 anume, o echip\u0103, un spital sau o regiune. De exemplu ar putea s\u0103 fie ineresa\u021bi de c\u00e2te ori o persona supraponderal\u0103 m\u0103n\u00e2nc\u0103 dulciuri sau dac\u0103 stresul \u00eei intensific\u0103 acest consum. Sau poate dori\u021bi s\u0103 afla\u021bi de c\u00e2te ori membrii unei echipe nu respect normele de igien\u0103 din spital, dac\u0103 este mai r\u0103u atunci c\u00e2nd personalul este insuficient sau dac\u0103 amorsele comportamentale joac\u0103 un rol. Sau poate vre\u021bi s\u0103 afla\u021bi care sunt sursele erorilor clinice \u0219i s\u0103 vede\u021bi care erori sunt mai commune \u00eentr-un anumit department. Sau la nivel de politici, ar putea s\u0103 fie important s\u0103 investig\u0103m dac\u0103 noile reglement\u0103ri cum ar fi interzicerea fumatului \u00een spa\u021biile publice au efect asurpa ratei fumatului.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pentru a r\u0103spunde la astfel de \u00eentreb\u0103ri a\u021bi putea s\u0103 \u00eentreba\u021bi direct persoanele implicate, dar este mai bine s\u0103 observa\u021bi direct comportamentul \u00een momente critice pentru a evita probleme de biasare sau uitare. Dezvoltarea tehnic\u0103 permite monitorizarea comportamentelor cu ajutorul smart phone-ului putem de exemplu s\u0103 vedem ce se petrece \u00een timp real. Un studio de tip n-of-1 ne ajut\u0103 s\u0103 r\u0103spundem la astfel de \u00eentreb\u0103ri.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Studiile de tip n-of-1 sunt utile c\u00e2nd o problem poate s\u0103 fie evaluat\u0103 cu <\/span><span style=\"font-weight: 400;\">m\u0103sur\u0103tori repetate<\/span><span style=\"font-weight: 400;\">, pentru a vedea schimbarea \u00een timp.\u00a0 Astfel putem s\u0103 descriem problema \u0219i s\u0103 vedem dac\u0103 se \u00eembun\u0103t\u0103\u021be\u0219te sau nu \u00een timp. Sau putem s\u0103 introducem o nou\u0103 interven\u021bie sau tratament pentru a vedea dac\u0103 are efectul scontat. Cea mai simpl\u0103 metod\u0103 de evaluare este un trend de observa\u021bii ca \u00een graficul din imaginea de mai jos. Acesta este un pas important \u00een analiza n-of-1. Adi\u021bional, exist\u0103 metode de <\/span><span style=\"font-weight: 400;\">analiz\u0103 statistic\u0103<\/span><span style=\"font-weight: 400;\"> pentru studiile de tip n-of-1. Metode mai complexe sunt \u00een curs de dezvoltate (de ex. <\/span><span style=\"font-weight: 400;\">Metode de a analiza schimbarea dinamic\u0103<\/span><span style=\"font-weight: 400;\">).\u00a0<\/span><\/p>\n<p><!--more--><\/p>\n<p><b>Utilizarea studiului n-of-1 pentru a evalua o problem\u0103<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Un studiu poate s\u0103 fie elaborate pentru a evaluarea severitatea sau frecven\u021ba unei probleme \u00een timp. \u00cen figura 1 nivelul anxiet\u0103\u021bii variaz\u0103 \u00een timp, dar putem s\u0103 identific\u0103m o tendin\u021b\u0103. C\u00e2nd am \u00eenregistrat \u0219i prezen\u021ba la munc\u0103, tendin\u021ba observat\u0103 este o diferen\u021b\u0103 \u00eentre weekend \u0219i cele cinci zile lucr\u0103toare. Acest fapt ne indic\u0103, c\u0103 persoana este mai anxioas\u0103 la munc\u0103 dec\u00e2t acas\u0103. Acest fap teste util atunci c\u00e2nd opt\u0103,m pentru un tratament optim pentru pacient. De exemplu, dac\u0103 evalu\u0103m dispozi\u021bia pe parcursul zilei pentru o personan\u0103 muribund\u0103 ne ajut\u0103 s\u0103 observ\u0103m tendin\u021bele care ajut\u0103 la ameliorarea depresiei. Informa\u021biile culese cu studii n-of 1 merg dincolo de simpla descriere a problemei \u0219i ajut\u0103 s\u0103 explic\u0103m ce observ\u0103m. Uneori practicienii au o teorie despre de au observant \u0219i acest tip de studio ajut\u0103 s\u0103 testeze c\u00e2t de bine explic\u0103 teoria ceea ce au observat. \u00cen cazul persoanei muribunde, putem s\u0103 monitoriz\u0103m g\u00e2ndurile \u0219i activit\u0103\u021bile pentru a confirma teoria c\u0103 dispozi\u021bia este influen\u021bat\u0103 de g\u00e2nduri \u0219i g\u00e2ndurile critice sunt associate cu activit\u0103\u021bile de diminea\u021b\u0103.\u00a0<\/span><\/p>\n<p><b>Figura 1:<\/b><span style=\"font-weight: 400;\"> utilizarea studiului N-of-1 pentru a descrie o problem\u0103: nivelul anxiet\u0103\u021bii cu albastru \u0219i zilele lucr\u0103toare cu ro\u0219u <\/span><i><span style=\"font-weight: 400;\">pe parcursul a 24 de zile<\/span><\/i><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1514\" src=\"https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-1.png\" alt=\"\" width=\"826\" height=\"447\" srcset=\"https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-1.png 826w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-1-500x271.png 500w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-1-768x416.png 768w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-1-230x124.png 230w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-1-350x189.png 350w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-1-480x260.png 480w\" sizes=\"(max-width: 826px) 100vw, 826px\" \/><\/p>\n<p><b>Utilizarea studiilor n-of-1 pentru a evalua \u00eembun\u0103t\u0103\u021birea sau \u00eenr\u0103ut\u0103\u021birea unei probleme \u0219i factorii determinan\u021bi\u00a0<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Problemele pot s\u0103 se \u00eembun\u0103t\u0103\u021beasc\u0103 sau \u00eentr\u0103ut\u0103\u021beasc\u0103 datorit\u0103 unor factori ca de exemplu o \u00eenmorm\u00e2ntare, o nunt\u0103, a \u0219tire media, \u00eenchiderea unei fabrici sau chiar vremea.\u00a0 Figura 2 este o repezentare ipotetic\u0103 a unui caz \u00een care o problem\u0103 medical\u0103 ca viroza a fost intensificat\u0103 \u00een s\u0103pt\u0103m\u00e2na de dup\u0103 o \u0219tire TV legat\u0103 de problem. Acest fapt sugereaz\u0103 c\u0103 intensificarea nu a fost determinat\u0103 de o epidemie \u0219i c\u0103 pe viitor, serviciile medicale pot anticipa o intensificare a consulta\u021biilor dup\u0103 ce viroza ajunge o \u0219tire la televizor. O analiz\u0103 de tip n-of-1 a statisticilor din spitalele britanice a ar\u0103tat efectele unui eveniment sportiv- a existat o cre\u0219tere a intern\u0103rilor pentru evenimente cardiace asociat\u0103 cu un meci important de fotbal \u00een timpul cupei din 1998.\u00a0<\/span><\/p>\n<p><b>Figure 2:<\/b><span style=\"font-weight: 400;\"> utilizarea studiilor n-of-1 pentru a surprinde efectul unui eveniment<\/span><b>: <\/b><i><span style=\"font-weight: 400;\">sunt aproximativ 40 de consulta\u021bii pe zi pentru viroz\u0103 \u00eenainte de emisiunea TV (vezi s\u0103geata albastr\u0103)<\/span><\/i> <i><span style=\"font-weight: 400;\">dup\u0103 care urmeaz\u0103 o intensificare a num\u0103rului de consulta\u021bii<\/span><\/i><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1515\" src=\"https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure2.jpg\" alt=\"\" width=\"879\" height=\"373\" srcset=\"https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure2.jpg 1082w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure2-500x212.jpg 500w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure2-768x326.jpg 768w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure2-830x352.jpg 830w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure2-230x98.jpg 230w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure2-350x148.jpg 350w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure2-480x204.jpg 480w\" sizes=\"(max-width: 879px) 100vw, 879px\" \/><\/p>\n<p><b>Using n-of-1 studies to assess whether an intervention or treatment is having the desired effect<\/b><\/p>\n<p><span style=\"font-weight: 400;\">N-of-1 methods may be used in <\/span><a href=\"https:\/\/www.bmj.com\/content\/337\/bmj.a1655\"><span style=\"font-weight: 400;\">the development of new interventions<\/span><\/a><span style=\"font-weight: 400;\">, including clinical and policy interventions.\u00a0 In the hypothetical example in figure 3, an obese patient is snacking approximately 7 times per day;\u00a0 following the intervention indicated by the red arrow (possibly self-monitoring of snacking), snacking quickly reduces to\u00a0 2 times per day.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Similar methods can be used to study a nation\u2019s <\/span><a href=\"http:\/\/www.smokinginengland.info\/\"><span style=\"font-weight: 400;\">smoking<\/span><\/a><span style=\"font-weight: 400;\">\u00a0 and assess the impact of policy changes such as the smoking ban in public places, e.g., <\/span><a href=\"http:\/\/www.smokinginengland.info\/\"><span style=\"font-weight: 400;\">how national policy affects smoking<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A good example of the practical use of N-of-1 methods to evaluate the effect of an intervention was reported by practitioners in a hospital district.\u00a0 They assessed the problem of delay in reporting adverse events for the period from 2001 to 2006 and found that, while delay varied, it was problematic for their patient safety programme and did not show signs of improvement over time. In 2007 and 2008 a program to recognise good performance was introduced which led to reduction in the delays for subsequent years and shows <\/span><a href=\"https:\/\/qualitysafety.bmj.com\/content\/20\/11\/974.long\"><span style=\"font-weight: 400;\">how such recognition improved timely reporting<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Figure 3: <\/span><b>Using n-of-1 studies to assess the effect of intervention:\u00a0 <\/b><i><span style=\"font-weight: 400;\">the first 15 days shows the frequency of snacking self-monitoring starting at day 16 (shown by the red arrow) results in reduced snacking<\/span><\/i><b>\u00a0<\/b><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1516\" src=\"https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-3.jpg\" alt=\"\" width=\"691\" height=\"355\" srcset=\"https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-3.jpg 691w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-3-500x257.jpg 500w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-3-230x118.jpg 230w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-3-350x180.jpg 350w, https:\/\/practicalhealthpsychology.com\/wp-content\/uploads\/2019\/10\/Figure-3-480x247.jpg 480w\" sizes=\"(max-width: 691px) 100vw, 691px\" \/><\/p>\n<p><b>Provoc\u0103ri\u00a0<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Colectarea de date este o provocare. M\u0103sur\u0103torile repetate sunt o dificultate \u0219i pot rezulta \u00een date lips\u0103. Dezvolt\u0103rile tehnologice ofer\u0103 posibilitatea s\u0103 utiliz\u0103m telefonul mobil sau sensori pentru a culege date mai u\u0219or.\u00a0<\/span><\/p>\n<p><b>Recomand\u0103ri practice<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Folosi\u021bi un studiu n-of-1 \u00een situa\u021bii practice<\/span>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Pentru a evalua \u0219i descrie o problem\u0103,\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Evalua efectele unui eveniment sau o interven\u021bie.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Evalua\u021bi o problem\u0103 care poate s\u0103 fie evaluat\u0103 prin m\u0103sur\u0103tori repetate \u00een timp<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Interpreta\u021bi datele utiliz\u00e2nd metode statistice descriptive \u0219i folosi\u021bi grafice\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Folosi\u021bi aplica\u021bii mart phone gratuite pentru a colecta date\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400;\">Translated by Dr. Irina Catrinel Cr\u0103ciun<\/span><\/i><\/p>\n<div id=\"gtx-trans\" style=\"position: absolute; left: 43px; top: 40px;\">\n<div class=\"gtx-trans-icon\"><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>By Marie Johnston and Derek Johnston, University of Aberdeen, Scotland Practitioners frequently want the answer to a problem which concerns one person, one health care team, one hospital or one region etc.\u00a0 For example, it may be important to know [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1522,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[32,13],"tags":[],"class_list":["post-1513","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-assessment","category-interventions"],"translation":{"provider":"WPGlobus","version":"3.0.2","language":"ro","enabled_languages":["en","id","my","bg","zh","hr","cz","da","de","es","fr","gr","he","it","ja","kr","lv","lt","hu","nl","no","pl","pt","ro","ru","sk","fi","sv","tr","uk"],"languages":{"en":{"title":true,"content":true,"excerpt":false},"id":{"title":true,"content":true,"excerpt":false},"my":{"title":true,"content":true,"excerpt":false},"bg":{"title":true,"content":true,"excerpt":false},"zh":{"title":true,"content":true,"excerpt":false},"hr":{"title":true,"content":true,"excerpt":false},"cz":{"title":true,"content":true,"excerpt":false},"da":{"title":true,"content":true,"excerpt":false},"de":{"title":true,"content":true,"excerpt":false},"es":{"title":true,"content":true,"excerpt":false},"fr":{"title":true,"content":true,"excerpt":false},"gr":{"title":true,"content":true,"excerpt":false},"he":{"title":true,"content":true,"excerpt":false},"it":{"title":true,"content":true,"excerpt":false},"ja":{"title":true,"content":true,"excerpt":false},"kr":{"title":true,"content":true,"excerpt":false},"lv":{"title":true,"content":true,"excerpt":false},"lt":{"title":false,"content":false,"excerpt":false},"hu":{"title":false,"content":false,"excerpt":false},"nl":{"title":true,"content":true,"excerpt":false},"no":{"title":false,"content":false,"excerpt":false},"pl":{"title":true,"content":true,"excerpt":false},"pt":{"title":true,"content":true,"excerpt":false},"ro":{"title":true,"content":true,"excerpt":false},"ru":{"title":true,"content":true,"excerpt":false},"sk":{"title":true,"content":true,"excerpt":false},"fi":{"title":true,"content":true,"excerpt":false},"sv":{"title":true,"content":true,"excerpt":false},"tr":{"title":true,"content":true,"excerpt":false},"uk":{"title":true,"content":true,"excerpt":false}}},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/posts\/1513","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/comments?post=1513"}],"version-history":[{"count":36,"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/posts\/1513\/revisions"}],"predecessor-version":[{"id":4603,"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/posts\/1513\/revisions\/4603"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/media\/1522"}],"wp:attachment":[{"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/media?parent=1513"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/categories?post=1513"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/practicalhealthpsychology.com\/ro\/wp-json\/wp\/v2\/tags?post=1513"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}