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href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6056150\/\">\u60a3\u8005\u306e\u5065\u5eb7\u30a8\u30f3\u30b2\u30fc\u30b8\u30e1\u30f3\u30c8\u30e2\u30c7\u30eb<\/a>\u3092\u63d0\u6848\u3057\uff0c\u79d1\u5b66\u7684\u306b\u691c\u8a3c\u3057\u307e\u3057\u305f\u3002\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u304f\u3053\u306e\u65b0\u3057\u3044\u5fc3\u7406\u5b66\u7684\u7406\u8ad6\u306f\u3001\u60a3\u8005\u30a8\u30f3\u30b2\u30fc\u30b8\u30e1\u30f3\u30c8\u304c\u751f\u307e\u308c\u308b\u30d7\u30ed\u30bb\u30b9\u3092\u60a3\u8005\u306e\u8996\u70b9\u304b\u3089\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30e2\u30c7\u30eb\u3067\u306f\u3001\u60a3\u8005\u30a8\u30f3\u30b2\u30fc\u30b8\u30e1\u30f3\u30c8\u3092\u30c0\u30a4\u30ca\u30df\u30c3\u30af\u306b\u5909\u5316\u3057\u7d9a\u3051\u308b\u30d7\u30ed\u30bb\u30b9\u3068\u6349\u3048\u3001\u4eba\u3005\u306f\u305f\u3068\u3048\u75c5\u6c17\u3068\u5171\u5b58\u3057\u3066\u3044\u3066\u3082\u3053\u3046\u3057\u305f\u6bb5\u968e\u3092\u7d4c\u3066\u81ea\u5206\u306e\u95a2\u5fc3\u4e8b\u3084\u76ee\u6a19\u3092\u9054\u6210\u3059\u308b\u80fd\u529b\u3092\u53d6\u308a\u623b\u3059\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u30e2\u30c7\u30eb\u306f\u3001\u60a3\u8005\u81ea\u3089\u306e\u9078\u629e\u306b\u3088\u3063\u3066\u3001\u6cbb\u7642\u306e\u53d7\u52d5\u7684\u306a\u53d7\u76ca\u8005\u304b\u3089\u6cbb\u7642\u7d4c\u9a13\u306e\u30d1\u30fc\u30c8\u30ca\u30fc\u3067\u3042\u308a\u526f\u64cd\u7e26\u58eb\u3067\u3042\u308b\u3068\u3044\u3046\u614b\u5ea6\u306b\u5909\u3048\u308b\u3053\u3068\u3092\u91cd\u8996\u3057\u3066\u3044\u307e\u3059\u3002\u60a3\u8005\u5f79\u5272\u306b\u304a\u3051\u308b\u3053\u306e\u5909\u5316\u306f\u3001\u5065\u5eb7\u72b6\u614b\u306b\u5bfe\u3059\u308b\u9069\u5fdc\u529b\u3068\u56de\u5fa9\u529b\u304c\u76f8\u4e92\u306b\u5f71\u97ff\u3057\u5408\u3046\u4e2d\u3067\u751f\u307e\u308c\u307e\u3059\u3002\u5b8c\u5168\u306a\u60a3\u8005\u30a8\u30f3\u30b2\u30fc\u30b8\u30e1\u30f3\u30c8\u306f\u3001\u60a3\u8005\u304c\u611f\u60c5\u3084\u610f\u6b32\u3092\u30d5\u30eb\u7a3c\u50cd\u3055\u305b\u3066\u81ea\u5206\u306e\u5065\u5eb7\u72b6\u614b\u3084\u5f79\u5272\u3001\u30a2\u30a4\u30c7\u30f3\u30c6\u30a3\u30c6\u30a3\u3092\u518d\u69cb\u6210\u3059\u308b\u3053\u3068\u304b\u3089\u751f\u307e\u308c\u308b\u306e\u3067\u3059\u3002\u60a3\u8005\u304c\u6cbb\u7642\u3068\u81ea\u5df1\u7ba1\u7406\u3092\u7d99\u7d9a\u3057\u3001\u884c\u52d5\u3084\u751f\u6d3b\u7fd2\u6163\u306e\u5909\u5bb9\u3092\u7dad\u6301\u3055\u305b\u308b\u305f\u3081\u306b\u60a3\u8005\u30a8\u30f3\u30b2\u30fc\u30b8\u30e1\u30f3\u30c8\u306f\u7121\u304f\u3066\u306f\u306a\u3089\u306a\u3044\u3082\u306e\u3067\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6056150\/\">\u60a3\u8005\u306e\u5065\u5eb7\u30a8\u30f3\u30b2\u30fc\u30b8\u30e1\u30f3\u30c8\u30e2\u30c7\u30eb<\/a>\u306b\u306f4\u3064\u306e\u30d5\u30a7\u30fc\u30ba\u304c\u3042\u308a\u3001\u533b\u7642\u5c02\u9580\u5bb6\u306f\u5404\u30d5\u30a7\u30fc\u30ba\u3067\u60a3\u8005\u306e\u30a8\u30f3\u30b2\u30fc\u30b8\u30e1\u30f3\u30c8\u3092\u652f\u63f4\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<ul>\n<li>\u30d5\u30a7\u30fc\u30ba1\uff1a\u60a3\u8005\u306f\u91cd\u5927\u306a\u30a4\u30d9\u30f3\u30c8\u3067\u3042\u308b\u75c5\u6c17\u306e\u8a3a\u65ad\u306b\u95a2\u3057\u3066\u5fc3\u7406\u7684\u306a\u3082\u308d\u3055\u3092\u7d4c\u9a13\u3057\u307e\u3059\u3002\u533b\u7642\u5f93\u4e8b\u8005\u306f\u60c5\u7dd2\u7684\u306a\u30b5\u30dd\u30fc\u30c8\u3092\u63d0\u4f9b\u3057\u3001\u60a3\u8005\u304c\u73fe\u5728\u306e\u5065\u5eb7\u72b6\u614b\u306b\u9806\u5fdc\u3059\u308b\u306e\u3092\u52a9\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u91cd\u8981\u306a\u306e\u306f\u3001\u60a3\u8005\u304c\u75c5\u6c17\u306b\u5bfe\u3057\u3066\u4e3b\u4f53\u6027\u3068\u7d71\u5236\u611f\u3092\u6301\u3066\u308b\u3088\u3046\u306b\u652f\u63f4\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u81ea\u5206\u306e\u884c\u52d5\u304c\u52b9\u679c\u7684\u306a\u5065\u5eb7\u7ba1\u7406\u306b\u3064\u306a\u304c\u308b\u3068\u60a3\u8005\u304c\u601d\u3048\u308b\u3088\u3046\u306b\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059\u3002<\/li>\n<li>\u30d5\u30a7\u30fc\u30ba2\uff1a\u60a3\u8005\u306f\u81ea\u5206\u306e\u5065\u5eb7\u72b6\u614b\u3092\u5206\u304b\u308a\u59cb\u3081\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u308c\u3092\u52b9\u679c\u7684\u306b\u7ba1\u7406\u3059\u308b\u65b9\u6cd5\u306b\u3064\u3044\u3066\u306f\u307e\u3060\u5341\u5206\u7406\u89e3\u3057\u3066\u306f\u3044\u307e\u305b\u3093\u3002\u3053\u306e\u6bb5\u968e\u3067\u60a3\u8005\u304c\u6cbb\u7642\u304b\u3089\u8131\u843d\u3059\u308b\u3053\u3068\u3082\u307e\u308c\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u533b\u7642\u5f93\u4e8b\u8005\u306f\u60a3\u8005\u304c\u4fa1\u5024\u5224\u65ad\u3059\u308b\u969b\u306b\u91cd\u8981\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u307e\u305f\u3001\u60a3\u8005\u304c\u81ea\u5206\u306e\u75c5\u6c17\u3092\u7ba1\u7406\u3057\u3001\u5bfe\u51e6\u3059\u308b\u3053\u3068\u3092\u652f\u63f4\u3057\u3001\u305d\u308c\u306b\u3088\u3063\u3066\u6cbb\u7642\u306e\u8131\u843d\u3092\u9632\u3050\u3053\u3068\u3082\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li>\u30d5\u30a7\u30fc\u30ba3\uff1a\u3053\u306e\u30d5\u30a7\u30fc\u30ba\u307e\u3067\u306b\u60a3\u8005\u306f\u81ea\u5206\u306e\u75c5\u6c17\u3092\u53d7\u3051\u5165\u308c\u3001\u75c5\u6c17\u306e\u767a\u75c7\u306b\u95a2\u3059\u308b\u5927\u304d\u306a\u5fc3\u7406\u7684\u82e6\u75db\u3092\u514b\u670d\u3057\u3066\u3044\u307e\u3059\u3002\u533b\u7642\u5f93\u4e8b\u8005\u306f\u30b9\u30c8\u30ec\u30b9\u306e\u591a\u3044\u72b6\u6cc1\u3084\u975e\u65e5\u5e38\u7684\u306a\u72b6\u6cc1\u3067\u3082\u60a3\u8005\u304c\u9069\u5fdc\u7684\u306a\u5065\u5eb7\u884c\u52d5\u3092\u7dad\u6301\u3067\u304d\u308b\u3088\u3046\u652f\u63f4\u3057\u307e\u3059\u3002<\/li>\n<li>\u30d5\u30a7\u30fc\u30ba4\uff1a<em>\u5e78\u798f\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3002<\/em>\u3053\u306e\u6700\u7d42\u6bb5\u968e\u3067\u60a3\u8005\u306f\u81ea\u5206\u306e\u75c5\u6c17\u3068\u305d\u306e\u610f\u5473\u3092\u5341\u5206\u306b\u7406\u89e3\u3057\u307e\u3059\u3002\u5f7c\u3089\u306f\u6cbb\u7642\u8981\u4ef6\u306b\u6cbf\u3063\u3066\u751f\u6d3b\u7fd2\u6163\u3092\u5909\u3048\u3001\u6162\u6027\u7684\u306a\u75c5\u3092\u62b1\u3048\u3066\u3044\u3066\u3082\u30dd\u30b8\u30c6\u30a3\u30d6\u3067\u6e80\u8db3\u306e\u3044\u304f\u751f\u6d3b\u306e\u8cea\u3092\u9054\u6210\u3059\u308b\u4e3b\u4f53\u7684\u306a\u884c\u70ba\u8005\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u533b\u7642\u5f93\u4e8b\u8005\u306f\u4fe1\u983c\u3067\u304d\u308b\u540c\u76df\u3067\u3042\u308a\u3001\u60a3\u8005\u306f\u6cbb\u7642\u30c1\u30fc\u30e0\u306e\u7a4d\u6975\u7684\u306a\u30e1\u30f3\u30d0\u30fc\u3067\u3042\u308b\u3068\u81ea\u899a\u3057\u3066\u3082\u3089\u3048\u308b\u3088\u3046\u652f\u3048\u307e\u3059\u3002<\/li>\n<\/ul>\n<p>\u5065\u5eb7\u3092\u7ba1\u7406\u3059\u308b\u305f\u3081\u306e\u53d7\u52d5\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u304b\u3089\u898f\u5247\u7684\u3067\u52b9\u679c\u7684\u306a\u884c\u52d5\u3092\u9078\u3076\u4e3b\u4f53\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u79fb\u884c\u3059\u308b\u306b\u306f\u3001\u610f\u5473\u3065\u3051\u3068\u81ea\u5df1\u540c\u4e00\u6027\u3092\u6df1\u3081\u3066\u3044\u304f\u8907\u96d1\u306a\u30d7\u30ed\u30bb\u30b9\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059\u3002\u60a3\u8005\u304c\u81ea\u5206\u81ea\u8eab\u306b\u3064\u3044\u3066\u6301\u3063\u3066\u3044\u308b\u4e3b\u89b3\u7684\u3067\u6642\u306b\u4e0d\u5408\u7406\u306a\u8a8d\u8b58\u3084\u3001\u81ea\u5206\u306e\u751f\u6d3b\u306e\u8cea\u3092\u8a55\u4fa1\u3059\u308b\u72ec\u81ea\u306e\u30ec\u30f3\u30ba\u306f\u3001\u30a8\u30f3\u30b2\u30fc\u30b8\u30e1\u30f3\u30c8\u306e\u3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